Wednesday, January 15, 2020

Genetic Engineering Pamphlet

Below are links that you can use as references for your Genetic Engineering Pamphlet:

Cloning
What is Cloning? from the Genetic Science Learning Center
How Cloning Works from How Stuff Works
Dolly the Sheep from the Roslin Institute
Dolly the Sheep from Live Science via Fox News

GMOs (Genetically Modified Organisms)
GMOs from Nature Education
GMOs from Encyclopedia Britannica
Are Biotech Foods Safe to Eat from WebMD
GMOs Pros and Cons from Healthline

Gene Therapy
Gene Therapy from the National Institute of Health
Gene Therapy Allows Children to Walk and Talk from the BBC
Gene Therapy for Genetic Disease from the American Society of Genes
Gene Therapy from the Mayo Clinic

Artificial Selection (Selective Breeding)
Artificial Selection from the University of California at Berkeley
Artificial Selection from National Geographic
Selective Breeding from Wikipedia
Selective Breeding from the BBC

Recombinant DNA (Gene Spicing)
Recombinant DNA from Encyclopedia Britannica
Gene Splicing from Reference.com
Uses of Recombinant DNA from Rensselaer Polytechnic Institute
Diagram of Recombinant DNA Process from The Biology Corner
Creating Recombinant DNA Diagram from GenomeEd

The Impact of Genetic Engineering on the Field of Medicine
Genetic Engineering and Vaccines from Vaccine Makers
Genetic Engineering and Insulin Production from the National Institute of Health
Genetic Engineering and Health from Nature
Proposed Treatment to Fix Genetic Diseases Raises Ethical Issues from NPR

The Impact of Genetic Engineering on the Field of Forensics
The Use of Genetics in Forensics from Bright Hub
DNA Profiling from Wikipedia
Uses of Genetic Engineering in Forensics from Yale Teachers Institute
How DNA Evidence Works from How Stuff Works

The Impact of Genetic Engineering on the Field of Agriculture
Genetic Engineeirng in Plant Crops from the Genetic Society of America
Genetic Engineering fin Agriculture from the USDA
Cheers for Cheerios from the NY Times
A Genetic Fix to Put the Taste Back in Tomatoes from the NY Times

Friday, March 22, 2019

Homeostasis WebQuest

Put your name on a sheet of notebook paper. Then complete the following tasks.   You will have one class day to complete Parts A to E. 

Part A- Homeostasis Overview and Body Temperature Regulation:
Watch an introductory video on homeostasis at Khan Academy:  Homeostasis at Khan Academy
(You can pause and rewind the video at any time.)

Answer the following questions:
1. Name TWO things the girl's body did to maintain homeostasis after she became too cold.
2. Name TWO things the girl's body did to maintain homeostasis after she became too warm.
3. Identify two other areas in which the body needs to maintain homeostasis.


Part B- Blood Sugar Regulation:
Visit Shmoop.com's article on homeostasis:  Shmoop Homeostasis Article

Complete the following:
4.  Find the diagram showing 5 parts of the Circle of Homeostasis.  As best as you can, draw this diagram showing the 5 parts and the fulcrum (seesaw). You do not need to add in the black and white text boxes, just focus on the colored part of the diagram.

At the bottom of the page is a section called Failure of Homeostasis which discusses what can happen if homeostasis goes wrong.
5. Identify the disease discussed in this section.
6. Briefly discuss what causes the disease.


Part C- pH Regulation:  
Visit the McGraw-Hill website section on homeostasis:  McGraw-Hill Summary of Homeostasis

Scroll down to the section on Control of pH and read it carefully.  Then answer the question:
7.  Identify the three ways the pH of the body is regulated.


Part D- Blood Pressure Regulation:
Read the answer to the question "How is my blood pressure normally regulated?" on How Stuff Works.

8. In one sentence, describe how your brain responds when your blood pressure drops too low.
9.  In two sentences, describe the two ways your kidneys regulate your blood pressure.


Part E- Water Balance Regulation:
Watch the Bozeman Science YouTube video on Osmoregulation.

10. What hormone has an effect on the nephrons in the kidneys and prevents excess water from being excreted?


Friday, October 19, 2018

The Role of the Ribosomes, ER, Golgi Apparatus, and Nucleus in Production of Proteins

Let's do a little review of basic cell structure.  The three main parts of the cell are: the plasma membrane, the nucleus, and the cytoplasm (with its associated organelles).


       In the enter of the cell is the nucleus, which holds DNA- the genetic material.  Every cell is contained within a membrane.  Plant cells also have a cell wall around the outside of the membrane while animal cells do not.  The cell wall provides protection to the plant cell as plants lack a skeleton. Inside the plasma membrane there is the cytoplasm (also called the cytosol).  The cytoplasm is not just a fluid, but rather a complex system of fibers, tubes, membranes, particles, and organelles (little organs), all of which have very specific functions.
   
    The relationship between three of these organelles- the ribosomes, the ER, and the Golgi- is very intricate.  Lets look a their functions one at a time.

     Ribosomes
            These are relatively tiny organelles. There are two kinds of ribosomes; free ribosomes (which float free in the cytoplasm), and bound ribosomes (which are attached to the endoplasmic reticulum).  Ribosomes are so important because they assemble amino acids into proteins.  If a protein is going to be used inside the cytoplasm of the cell, it is generally built by free ribosomes and not by ones bound to the endoplasmic reticulum.

     Endoplasmic Reticulum
        This brings us to an organelle called the Endoplasmic Reticulum.  Scientists call it ER for short.  There are two different kinds of ER,  Smooth ER and Rough ER.


 
            Smooth ER is not involved in protein synthesis.  It is the site of the synthesis of fatty acids and phospholipids.  It is called "smooth" because it has no ribosomes on its surface.  It is shaped like a network of little tubes.

            Smooth ER creates steroids and stores ions so that the cell can have them when its needs them.  Smooth ER's enzymes catalyze many different reactions.  It detoxifies poisonous substances in the liver, for example.  Smooth ER is associated with drug tolerance.  Alcoholics have a lot more smooth ER than people who don't drink.  As people consume more alcohol, they realize they have to drink more to get the same effect.  This happens because more inactivating enzymes are being produced.  These inactivating enzymes are responsible for helping to detoxify the liver.  A body's production of more smooth ER is one example of how your body tries to maintain homeostasis by protecting you from the toxic effects of alcohol.

            Rough ER gets its name because it is studded (covered) with ribosomes,which makes it look "rough" under a microscope.  These ribosomes are said to be "bound" to the ER.  The largest number of bound ribosomes is found in cells that produce enzymes to be secreted, which means they are made for delivery outside of the cell into the body.

             Once a protein has been synthesized (made), rough ER creates a bubble around it by pinching off a portion of its own membrane.  This bubble is called a transition vesicle.  The transition vesicle then moves to either the cell membrane or to the Golgi apparatus.

            The Golgi Apparatus was named for Camillo Golgi, the Italian physician who discovered it.  It is also referred to as the Golgi Body, the Golgi Complex, or simply the Golgi to avoid confusion.  The Golgi looks like a loose stack of pancakes.  Plant cells contain many of these stacks, while animals cells contain less.



         The Golgi takes simple molecules it gets from the Rough ER and makes them larger.  Remember the vesicles?  These vesicles or 'transporter packages' have their contents modified inside the Golgi.  After these little packages get modified, they get 'addressed' for delivery to their next destination.  The packages that now carry the modified contents are  called secretory vesicles. The Golgi is the final link in the relationship between the ribosomes, ER, and Golgi.




             IN SUMMARY:
              - Proteins are made in ribosomes.
              - Rough ER sends simple protein molecules to the Golgi Apparatus in transition vesicles.
              - The Golgi absorbs these transition vesicles through one side of its membrane.
              - The Golgi takes the simple molecules and converts them into larger macromolecules.
                      The larger molecules get packaged into secretion vesicles.
               - The Golgi then releases these secretion vesicles out of the other side into the
                      cytoplasm.
               -  From there, the secretion vesicles move onto the cell membrane and are released out
                     of the cell.





Tuesday, June 5, 2018

Field Research Slides Template

MAKE A COPY of the Slides template into your Google Drive using a new name. 
SHARE the new presentation with ALL GROUP MEMBERS and Mrs. Keller at nkeller@penncrest.org.
Make sure all group members have permission to edit.
The presentation should be exactly 9 slides long in the order given.
Do not add, remove, or rearrange slides.

Field Research Slides Template

Monday, January 30, 2017

Amoeba Sisters Genetics Review Videos

Instructions:

1. Follow the links below.
OR
Go to YouTube on your iPad. Search for Amoeba Sisters. Watch the following videos by the Amoeba Sisters by searching for the name of the video.

2. It is most helpful to watch the videos in the order listed on the paper.

3. As you watch each video, write down one thing you learned from the video that you did not learn in class in the correct place on the handout.

Video 1- Meiosis: The Great Divide

Video 2- Chromosome Numbers During Division: Demystified!

Video 3- Punnett Squares and Sex-Linked Traits

Video 4- Multiple Alleles (ABO Blood Groups) and Punnett Squares

Video 5- Incomplete Dominance, Co-Dominance, Polygenic Traits, and Epistasis

Video 6- Mutations: The Potential Power of a Small Change


WHEN YOU ARE DONE PLEASE MAKE SURE YOUR NAME IS ON YOUR PAPER AND TURN IT IN!

Wednesday, November 9, 2016

Cell Transport STEM Activity 11/22/16

You will need:
-  Biology Textbook                - iPad              - Headphones          - Composition Notebook

Title the next page of your composition notebook Cell Transport Activity.  Follow the instructions to complete the introductory activity on Cell Transport.  Write the answers to the questions in your composition notebook.  You do not need to write the questions.

1. Turn to page 208 in your textbook. Read the THINK ABOUT IT section at the top of the page.
What does the book compare the cell membrane to in the analogy?

2. Look at the bold print by the blue key on page 209.  Define the term passive transport.

3. Go back to page 208 and find the word Diffusion in blue.  Read this section. Answer the following questions:
         A. What does the cytoplasm consist of?
         B. How do particles tend to move?
         C. What is the name given to this process?
         D. What term is given to a solution when the concentration of substances is the same on both sides of a membrane?

4. Look down a the second half of page 209.  Read this section and answer the following questions:
        A. What type of molecule passes easily through the cell membrane?
        B. Define the term facilitated diffusion.
        C. From page 209, identify a molecule that moves through a membrane by facilitated transport.
       D. Turn to page 210.  Identify a second molecule that new research shows moves by facilitated diffusion.
        E. Using Figure 7-16, draw a sketch to show this specialized protein.  Label the cell membrane, the water, and the aquaporin in your diagram and give it a title..

5. Find the term osmosis in bold print on page 210.  Define the term osmosis.

6. Read the paragraph at the bottom of page 210, and examine Figure 7-18.  There are three types of conditions a cell can face- isotonic, hypertonic, and hypotonic.  For each condition:
      A. Define the condition.
      B. Draw a simple picture of the cell (plant or animal) and use arrows to show the movement of water.

7. Watch the Amoeba Sisters video on Osmosis: A Solute and Solvent Love Story


Answer the questions:
A) What happens to a salt water fish if you put it in fresh water?
B) Explain why putting salt on a slug kills the slug.

8. Turn to page 212.  Find the bolded words next to the blue key.  Define the term active transport.

9. What does active transport require? (Use a one word answer.)

10. What carries out active transport of small molecules or ions across a cell membrane?

11. Identify 3 types of ions moved by the proteins pumps.

12. Look at Figure 7-19.  Where does the energy to drive these pumps come from?

13.  How do the pumps move the ions across the membrane?

14.  Look at page 213.  There are two types of bulk transport- endocytosis and exocytosis.  Distinguish between endocytosis and exocytosis and draw a simple picture of each process.

15.  Examine Figure 7-20.  What is being taken into the white blood cell by mean of endocytosis?

16. Complete the Membrane Channels simulation from PhET.
        1) Download and open the simulation.
        2) Click the Show Concentrations box on the right.
        3) Using the top red button on the left, add 30 green molecules to the top of the membrane.
        4) Using the bottom red button on the left, add 30 blue molecules to the top of the membrane.
        5) Notice the size of the green and blue bars on the bar graph on the right.  This compares the concentrations of the green and blue molecules.
        6) Click and drag a green gated channel and a blue gated channel up to the yellow membrane.
        7) Open the channels by using the button on the top right.
        8) Watch the bars in the bar graph.
Answer the questions:
         A) What happened to the concentrations of the molecules after a few minutes?
         B) Why could you have predicted this would happen?












Monday, October 17, 2016

Cell Theory STEM Biology Activity 10/18/16

1) Title this section of your Composition Notebook "Cell Theory"

2) Then write, "Three Parts of the Cell Theory," visit Study.com- Cell Theory  and list the 3 parts.

3) -Create a chart in your Composition Notebook.
-It should have three columns: Scientist, Summary of Work, Date of Work.
-In the Scientist column, fill in the names of the following scientists (leave about 1.5 inches of space between each one): Hans and Zaccharias Janssen, Anton Van Leeuwenhoek, Robert Hooke, Matthias Schleiden, Theodore Schwann, Carl Heinrich Braun, Rudolph Virchow, and Walther Flemming.
-Title your chart, "Scientists Contributing to the Cell Theory."

4) As you visit the following sites, complete the chart to fill in the missing information.  Not all scientists will be discussed on all sites.

View the video on:  The Wacky History of the Cell Theory

Examine the timeline at: Cell Theory Timeline

Read about the History of Biology: Cell Theory

Examine the quick summary of the Cell Theory


5) Title the next section "Modern Cell Theory." View the Wikipedia entry on Cell Theory.   List the three modern additions to the cell theory which are generally accepted.

6) In 2 sentences, discuss one time there was a disagreement among scientists during the development of the Cell Theory.




Monday, June 6, 2016

STEM- Brine Shrimp Lab, Final Day

This will be the final day for the Brine Shrimp Lab. 


You should already have the following in your Composition Notebook:


A section titled, "Brine Shrimp Lab."

Background -(10 sentences of research about brine shrimp) 


Problem- (Stated as a question)


Hypothesis- (What you are predicting what will happen in your experiment)


Materials- (A list of the materials you will need for your experiment)


Procedure/Experiment- (A list of numbered steps explaining how you set up your experiment)


Diagram- (OPTIONAL- a sketch showing your experimental setup)




Today you will need to add the following sections:


Data- A data table comparing the data collected in your experiment.  It should have a title and clearly labeled columns with units if applicable. 

Graph- A graph comparing the data collected in your data table.  Don't forget a title and label your X and Y axis. 

Conclusion- 4 or 5 sentences analyzing the results of your experiment.  Was your hypothesis supported or not supported by your data?   Explain and elaborate. 

Tuesday, May 31, 2016

STEM Brine Shrimp Lab- Day 2

Today you are going to design an experiment to test a variable of your choice relating to brine shrimp.

Suggestions for variables  (or come up with your own area) that affect the hatching rate of brine shrimp eggs:
     - Temperature
     - Salinity (salt content) of the water
     - Size of container
     - Type of container
     - Ratio of eggs to water

If you are working with salinity, a heaping spoonful of salt in a liter of spring water will give you a salt concentration of 25 parts per thousand.   You can vary the amount of salt to change the concentration.

In your composition notebook you should already have a this lab titled and a 10 sentence section titled 'Background.'

Working with your group members you job today is to come up with your:

Problem- (Stated as a question)

Hypothesis- (What you are predicting what will happen in your experiment)

Materials- (A list of the materials you will need for your experiment)

Procedure- (A DETAILED NUMBERED list of the steps of your experiment)

On the index card Mrs. Keller provides, write a list of materials your group will need for Thursday.  Be complete and specific as possible. Turn this in to Mrs. Keller. 

Friday, May 13, 2016

STEM Brine Shrimp Lab- Introduction and Research

After Keystone testing is over, we will do our final project of the year, Brine Shrimp.



You may have seen brine shrimp marketed as "Sea Monkeys" or even had some when you were a kid!



Today you will need to do some background research with brine shrimp so that you have a depth of understanding necessary to do your lab work.

Title this section of your composition notebook, "Brine Shrimp Lab."

Underneath the this, title the first section, "Background."   Then visit the following links to learn more about brine shrimp.  Write a 10-sentence paragraph summarizing what you learned about brine shrimp.

Brine Shrimp from Learn Genetics

Brine Shrimp from the Great Salt Lake Ecosystem Project

Brine Shrimp in the Great Salt Lake of Utah

Brine Shrimp from Wikipedia


After you are done with your research, think about who you would like to work with in your group (groups of 3 to 4 are good), and in what area your might like to conduct your research.  You might research one of the following areas (or come up with your own area) that affect the hatching rate of brine shrimp eggs:
     - Temperature
     - Salinity (salt content) of the water
     - Size of container
     - Type of container
     - Ratio of eggs to water

After the Keystones you will come together in your group, formulate a hypothesis, and design and complete an experiment to test your hypothesis.